What are the subtle signs of MACLD progression?
| Estimated time to read:
The following content is part of a paid sponsorship and is not an endorsement by CHEST nor does it reflect the views or opinions of CHEST.

It may be difficult to spot gradual changes that can signal MAC lung disease progression: shifts in symptoms, quality of life, radiographic findings, and changes in microbiologic patterns.1-6
For patients with MAC lung disease, subtle changes can be early signs of progression—and progression can lead to disease advancement. Recognizing subtle changes sooner may help you identify appropriate patients with MAC lung disease progression.1,2
Visit SpotMACprogression.com to learn how to spot MAC lung disease progression.
MAC=Mycobacterium avium complex; MACLD=MAC lung disease.
References: 1. van Ingen J, et al. Expert Rev Respir Med. 2021;15(11):1387-1401. doi:10.1080/17476348.2021.1987891 2. Hagiwara E, et al. Respir Investig. 2019;57(1):54-59. doi:10.1016/j.resinv.2018.08.006 3. Lin C-Y, et al. Front Microbiol. 2022;13:868435. doi:10.3389/fmicb.2022.868435 4. Daley CL, et al. Clin Infect Dis. 2020;71(4):e1-e36. doi:10.1093/cid/ciaa241 5. Lee G, et al. Ann Am Thorac Soc. 2013;10(4):299-306. doi:10.1513/AnnalsATS.201303-062OC 6. Pan SW, et al. Clin Infect Dis. 2017;65(6):927-934. doi:10.1093/cid/cix479
© 2026 Insmed Incorporated. All Rights Reserved. Insmed is a registered trademark, and Spot MAC Progression and associated logo are trademarks, of Insmed Incorporated. NP-NTM-US-00307



