Innovating Care for Chronic Respiratory Diseases: Targeting IL-33 and Epithelial Alarmins

Marriott Marquis, Great Lakes ABC
Sponsored by National Jewish Health. Supported by an educational grant from AstraZeneca.

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Program Description

Recent studies have emphasized the role of epithelial alarmins—particularly IL-33—in driving immune responses and exacerbations in chronic respiratory diseases such as asthma, COPD, and acute viral respiratory infections. IL-33 stands out due to its dual role in type-2 immune responses and antiviral defense mechanisms. IL-33 not only amplifies inflammation during viral infections like influenza and SARS-CoV-2 but also contributes to chronic airway remodeling and dysfunction. Understanding the interactions among IL-33, IL-25, and TSLP can unlock novel insights into respiratory disease pathophysiology and inform innovative therapeutic strategies.

This CME breakfast symposium, presented by National Jewish Health, will bring together leading pulmonologists, allergists/immunologists, and critical care specialists for a moderated panel to explore multidisciplinary perspectives on IL-33 and other epithelial alarmins in respiratory disease management. The panel will discuss real-world clinical cases to deepen attendees’ understanding of respiratory pathophysiology and guide the application of evidence-based strategies to personalize patient care.

1.0 CME/MOC

Register at: NJHealth.org/IL33EpithelialAlarmins

This symposium is not supported, endorsed, or accredited by the American College of Chest Physicians.

Panelists

Katharine M. Woessner, MD, FAAAAI
Scripps Health
Allergy, Asthma and Immunology
Clinical Professor of Medicine
San Diego, California

Scripps Health
Allergy, Asthma and Immunology
Division Head
San Diego, California

Monica Kraft, MD
Icahn School of Medicine at Mount Sinai
Samuel Bronfman Department of Medicine
System Chair
New York, New York

Icahn School of Medicine at Mount Sinai
Samuel Bronfman Department of Medicine
Murray M. Rosenberg Professor of Medicine
New York, New York

William J. Janssen, MD
National Jewish Health
Reilley Chair of Lung Injury, Repair and Interstitial Disease
Denver, Colorado

National Jewish Health
Section of Critical Care Medicine
Professor of Medicine
Denver, Colorado

National Jewish Health
Section of Critical Care Medicine
Section Head
Denver, Colorado

Moderator

Rohit Katial, MD, FAAAAI, FACAAI, FACP
National Jewish Health
Division of Allergy & Clinical Immunology
Professor of Medicine
Denver, Colorado

National Jewish Health
Associate Vice President of Education
Denver, Colorado

National Jewish Health
Center for Clinical Immunology
Director
Denver, Colorado