Thoracic Oncology
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Exploring the evolving landscape in combination therapies for EGFR-mutated advanced NSCLC
Susan Scott, MD, discussed the findings from the MARIPOSA and FLAURA2 trials and the next steps to identify who may benefit from which regimen.
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FDA proposal would eliminate addicting power of cigarettes, other combustible tobacco products
While the rule could reduce smoking rates, Sven-Eric Jordt, PhD, said clinicians must remember that low-nicotine cigarettes still expose those who smoke to carcinogens.
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Managing central airway obstruction
New guidelines on central airway obstruction standardize diagnosis and management recommendations, emphasizing therapeutic bronchoscopy, rigid bronchoscopy, and multidisciplinary care.
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Rethinking tobacco use to include all forms of nicotine delivery
Frank Leone, MD, MS, FCCP, said clinicians must reframe how they think about tobacco product use—and how to treat it.
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White ribbons around CHEST HQ raise awareness for lung cancer screening and early detection
During the month of November, CHEST displayed white ribbons around its headquarters in Glenview, Illinois, to raise awareness for lung cancer screening and early detection.
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Revival of the aspiration vs chest tube debate for PSP
Considerable heterogeneity exists in the management of primary spontaneous pneumothorax (PSP). American and European guidelines have been grappling with this question for decades: What is the best way to manage PSP? A 2023 randomized, controlled trial (Marx et al. AJRCCM) sought to answer this. The study recruited 379 adults aged 18 to 55 years between…
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Lung ultrasound: An indispensable yet underutilized tool
An assessment using bedside thoracic ultrasound (TUS) improves diagnostic evaluation and therapeutic management in critically ill patients without undue risk. With changes in diagnosis occurring in 23% of cases and alterations in management in 39% of critically ill patients, TUS can improve length of stay, reduce complications, minimize delays in therapy, and lower hospitalization costs.1…
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Atypical pulmonary cysts: Why to care
Since the American College of Radiology (ACR) updated its Lung CT Screening Reporting & Data System (Lung-RADS) to include atypical pulmonary cysts in 2022, there has been little discussion among chest physicians regarding the significance of pulmonary cysts and why these changes were made. Lung-RADS 2022 defined atypical pulmonary cysts as single, unilocular cysts with…
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Diagnostic yield reporting of bronchoscopic peripheral pulmonary nodule biopsies: A call for standardization
More than 1.5 million Americans are diagnosed with an incidental CT scan-detected lung nodule annually. Advanced bronchoscopy, as a diagnostic tool for evaluation of these nodules, has evolved rapidly, incorporating a range of techniques and tools beyond CT scan-guided biopsies to assess peripheral lesions. The primary goal is to provide patients with accurate benign or…
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Electrical impedance tomography: Visualization and integration of the impact of mechanical ventilation
Lung protective ventilation (LPV) is the cornerstone to minimizing ventilator-induced lung injury. Hence, LPV is associated with better survival in patients both with and without ARDS.1 2 3 Continuous monitoring of the tidal volume, plateau pressure, and positive end-expiratory pressure (PEEP) is crucial to maintain LPV. Electrical impedance tomography (EIT) is a noninvasive, radiation-free, imaging…
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Primary vs secondary: A review of pneumothorax management
Optimal management of primary spontaneous (PSP) and secondary spontaneous pneumothorax (SSP) remains an area of ongoing debate, with both CHEST and the British Thoracic Society (BTS) offering guidelines to address management decisions. The consensus for treatment of PSP depends on the size of the pneumothorax; if smaller than 2-3 cm, the patient can be observed…
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A word of caution on e-cigarettes: Retracted paper
Editor’s note: On March 29, 2024, the authors of the study, “Efficacy of Electronic Cigarettes vs Varenicline and Nicotine Chewing Gum as an Aid to Stop Smoking: A Randomized Clinical Trial,” published in JAMA Internal Medicine, issued a formal retraction of their article. The CHEST Physician Editorial Board apologizes for any confusion this may have…
