News
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FDA approval of oveporexton for narcolepsy allows clinicians to treat more than symptoms
When the US Food and Drug Administration approved the drug in August, oveporexton became the first agent to target the loss of orexin signaling that causes narcolepsy type 1.
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Study shows association between higher vitamin A levels and better lung function
The results linked higher vitamin A levels with better lung function in children and adults with asthma, while vitamin D showed a similar association primarily in adults.
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Point-of-care respiratory virus testing in nursing homes could reduce transfers to EDs
A recent study showed that onsite POC-RM-PCR testing resulted in an 11% absolute reduction in the probability of emergency department transfer during an outbreak.
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Low-nicotine cigarettes unlikely to trigger sustained compensatory smoking, meta-analysis finds
Hasmeena Kathuria, MD, said the findings provide further support that very low nicotine content cigarettes do not lead to substantially increased smoking or carbon monoxide exposure.
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Selpercatinib improves event-free survival in early-stage RET fusion-positive NSCLC
Alexander E. Drilon, MD, discusses the findings from the first randomized phase 3 trial to evaluate a RET kinase inhibitor as adjuvant therapy in RET fusion-positive lung cancer.
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Intensive antiviral chemoprophylaxis in nursing homes reduces hospitalization
“The actionable message is not to aim for 100%; it is to reach the most residents in the first 48 hours,” said Viren Kaul, MD, FCCP.
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Remote patient monitoring shows no benefit after serious infections, major trial finds
Researcher Sachin Yende, MD, MS, said the results challenge the assumption that remote monitoring alone improves postdischarge outcomes.
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Limited data on GLP-1RAs show early promise in PAH
A review led by Benoît Aguado, MD, explores several mechanisms that could make GLP-1 receptors relevant to pulmonary vascular disease.
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When PH and ILD meet: From overlap to a unified disease paradigm
For clinicians, the shift in the PH-ILD space demands a broader perspective that integrates vascular and parenchymal disease, emphasizes early detection, and prioritizes multidisciplinary care.
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Study demonstrates superior protection from mRNA influenza vaccine compared with standard-dose vaccines
Experts caution that further research is needed to evaluate the platform’s performance across multiple seasons and compare it with enhanced vaccines.
