News
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Setidegrasib demonstrates durable responses in KRAS G12D-mutant NSCLC
Coauthor Anup Kasi, MD, MPH, said the study represents an important step forward in the development of KRAS G12D-targeted therapies.
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Study links isoflavone intake to reduced COPD morbidity
Mariah K. Jackson, PhD, RDN, LMNT, said that while the research does not establish causality, nutrition is generally a safe, well-tolerated, and cost-effective strategy to improve respiratory health.
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New portable, accurate TB test may broaden access
International TB specialist Alfred A. Lardizabal, MD, said he believes the development will empower resource-limited communities by bringing TB diagnostic capacity closer.
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Large trial finds no advantage for balanced fluids over saline in pediatric sepsis
Investigators Fran Balamuth, MD, PhD, MSCE, and Scott L. Weiss, MD, MSCE, said the results support the use of either therapy for initial sepsis resuscitation in children.
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Coadministration safety of influenza, pertussis vaccines during pregnancy confirmed by large data set
Experts said the results, which showed no difference in outcomes such as preterm birth and low birth weight, may help improve prenatal vaccine uptake by reducing additional appointments for patients.
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HI-PEITHO confirms benefit of USCDT in intermediate-risk pulmonary embolism
Investigator Frederikus A. Klok, MD, PhD, said he expects additional evidence to be published in the coming year, which will shape future guidelines and clinical management of patients with intermediate-high risk pulmonary embolism.
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Study evaluates sleep efficiency change in patients with pediatric OSA following adenotonsillectomy
Pediatric pulmonologist Anne C. Coates, MD, said it may take longer to see a benefit from surgery in some populations, especially when nonrespiratory factors may be affecting sleep efficiency.
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The evolution of interventional pulmonology
Interventional pulmonology has rapidly evolved into a technology-driven specialty, with advances like robotic bronchoscopy and real-time imaging enabling safer, more precise access to peripheral lung lesions. These innovations allow clinicians to combine diagnostic and therapeutic procedures in a single setting.
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Hypoxic burden from sleep apnea may predict peri-operative outcomes better than AHI
Recent results show that sleep apnea-specific hypoxic burden could help inform clinicians whether a patient can safely receive standard postoperative monitoring, said Andrey Zinchuk, MD, MHS.
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HFOV outperformed conventional ventilation for neonatal ARDS in trial
While the results need to be verified in larger, multicenter populations, new data show high-frequency oscillatory ventilation reduced the incidence of bronchopulmonary dysplasia in preterm infants.
