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Critical Care

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  • Study supports 30 mL/kg or more of initial fluid for sepsis-induced hypoperfusion

    Study supports 30 mL/kg or more of initial fluid for sepsis-induced hypoperfusion

    Researchers also analyzed weight-based fluid resuscitation recommendations and found that, regardless of the approach, administration of 30 mL/kg of fluid was associated with reduced mortality.


  • 2026 Surviving Sepsis Campaign: Applying guidelines at the bedside

    2026 Surviving Sepsis Campaign: Applying guidelines at the bedside

    The guidelines distill available evidence into actionable recommendations to help clinicians navigate complex sepsis management processes and treat patients.


  • When everyone nods but no one understands

    When everyone nods but no one understands

    As critical care evolves, one of our greatest responsibilities is to ensure that patients and families have a clear and comprehensive understanding of their condition and care plan.



  • MARCH trial challenges routine use of mucoactive therapies in mechanically ventilated patients

    MARCH trial challenges routine use of mucoactive therapies in mechanically ventilated patients

    Jesse Hall, MD, said the safety findings revealed “clinically significant events and tip the balance from ‘no benefit’ to ‘no benefit and likely harms.’”


  • Study links birth sites with lower levels of service to higher odds of resuscitation interventions

    Study links birth sites with lower levels of service to higher odds of resuscitation interventions

    While factors such as socioeconomic status and remoteness were not associated with higher odds of interventions, lower-level birth sites were associated with higher odds of chest compressions.


  • Large trial finds no advantage for balanced fluids over saline in pediatric sepsis

    Large trial finds no advantage for balanced fluids over saline in pediatric sepsis

    Investigators Fran Balamuth, MD, PhD, MSCE, and Scott L. Weiss, MD, MSCE, said the results support the use of either therapy for initial sepsis resuscitation in children.


  • The evaluation and management of OSA in medically hospitalized patients

    The evaluation and management of OSA in medically hospitalized patients

    These recommendations will hopefully prompt institutions to develop protocols for screening, diagnosing, and potentially offering PAP therapy to this patient population.


  • Advancing postarrest care in the ICU

    Advancing postarrest care in the ICU

    New evidence suggests prophylactic antibiotics and biomarkers like neuron-specific enolase may help improve prevention and prognostication of cardiac arrest, offering a more proactive approach to postarrest care.



  • The evolution of interventional pulmonology

    The evolution of interventional pulmonology

    Interventional pulmonology has rapidly evolved into a technology-driven specialty, with advances like robotic bronchoscopy and real-time imaging enabling safer, more precise access to peripheral lung lesions. These innovations allow clinicians to combine diagnostic and therapeutic procedures in a single setting.


  • Hypoxic burden from sleep apnea may predict peri-operative outcomes better than AHI

    Hypoxic burden from sleep apnea may predict peri-operative outcomes better than AHI

    Recent results show that sleep apnea-specific hypoxic burden could help inform clinicians whether a patient can safely receive standard postoperative monitoring, said Andrey Zinchuk, MD, MHS.