Asthma
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COURSE trial shows importance of biomarker testing in COPD
While overall the trial was negative, Meilan King Han, MD, MS, and Sanjay Ramakrishnan, MBBS, PhD, said it demonstrated the promise of tezepelumab for patients with baseline blood eosinophil counts ≥ 150 cells/µL.
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Dupilumab reverses airway inflammation, mucus hypersecretion in type 2 asthma
Lead author Mario Castro, MD, MPH, FCCP, said the VESTIGE trial is one of the first to show that we can reverse the disease process in asthma and substantially improve lung function.
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Hope on the horizon for bronchiectasis
The combination of personalized therapies, novel and repurposed medications, and a multidisciplinary approach is transforming bronchiectasis from a condition that once had few treatment options into one that offers hope for improved management and even disease stabilization.
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SWIFT studies show promise of IL-5-targeted twice-yearly option for severe asthma with an eosinophilic phenotype
Lauren E. Eggert, MD, said depemokimab could be a more convenient therapy choice for both patients and providers.
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Study to test efficacy of tezepelumab for treating asthma exacerbations in the emergency department
Diego J. Maselli, MD, FCCP, said the TERAA trial will provide needed evidence on the use of biologics in the acute care setting.
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Tezepelumab trial demonstrates solid results for treatment of CRSwNP
Joseph K. Han, MD, said the data showed the highest change in sinonasal outcome test scores from baseline compared with any other biologic studies for chronic rhinosinusitis with nasal polyps.
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Study demonstrates viability of biologics for severe asthma, COPD exacerbations in eosinophilic inflammation
While larger studies are needed, Dharani K. Narendra, MD, FCCP, said the findings from the ABRA trial could be a game changer and reduce the need for glucocorticoids for some patients.
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Growing evidence links perinatal exposures and childhood asthma risk
Research by Christian Rosas-Salazar, MD, MPH, is improving understanding of mechanisms at play from such exposures as antibiotics, RSV, tobacco smoke, and more.
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Consequences of wildfire smoke exposure extend beyond local area
In a recent study, Mary E. Maldarelli, MD, and colleagues demonstrated that wildfires can increase health risks even from thousands of miles away.
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Mitigating risk of asthma emergencies during respiratory season
During flu season, asthma emergencies become a heightened concern, especially among children. Proactive measures including vaccination, updated asthma action plans, and access to quick relief medications are critical.
