Critical Care
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Study supports 30 mL/kg or more of initial fluid for sepsis-induced hypoperfusion
Researchers also analyzed weight-based fluid resuscitation recommendations and found that, regardless of the approach, administration of 30 mL/kg of fluid was associated with reduced mortality.
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2026 Surviving Sepsis Campaign: Applying guidelines at the bedside
The guidelines distill available evidence into actionable recommendations to help clinicians navigate complex sepsis management processes and treat patients.
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Rethinking vascular access in the ICU: The rise of peripheral vasopressors
Peripheral vasopressors are no longer an exception reserved for minutes before central access is obtained; they have become common practice nationwide.
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When everyone nods but no one understands
As critical care evolves, one of our greatest responsibilities is to ensure that patients and families have a clear and comprehensive understanding of their condition and care plan.
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MARCH trial challenges routine use of mucoactive therapies in mechanically ventilated patients
Jesse Hall, MD, said the safety findings revealed “clinically significant events and tip the balance from ‘no benefit’ to ‘no benefit and likely harms.’”
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Study links birth sites with lower levels of service to higher odds of resuscitation interventions
While factors such as socioeconomic status and remoteness were not associated with higher odds of interventions, lower-level birth sites were associated with higher odds of chest compressions.
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Impossible choices: Goal-concordant care in the ICU
Clinicians should approach discussions about goal-concordant care with curiosity, humility, and responsibility, for the benefit of both the patient and their family.
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Large trial finds no advantage for balanced fluids over saline in pediatric sepsis
Investigators Fran Balamuth, MD, PhD, MSCE, and Scott L. Weiss, MD, MSCE, said the results support the use of either therapy for initial sepsis resuscitation in children.
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The evaluation and management of OSA in medically hospitalized patients
These recommendations will hopefully prompt institutions to develop protocols for screening, diagnosing, and potentially offering PAP therapy to this patient population.
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Ventilatory management of immune checkpoint inhibitor pneumonitis
As immune checkpoint inhibitor use continues to expand, prospective data on phenotype-guided management and extracorporeal membrane oxygenation selection criteria are urgently needed.
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Advancing postarrest care in the ICU
New evidence suggests prophylactic antibiotics and biomarkers like neuron-specific enolase may help improve prevention and prognostication of cardiac arrest, offering a more proactive approach to postarrest care.
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The evolution of interventional pulmonology
Interventional pulmonology has rapidly evolved into a technology-driven specialty, with advances like robotic bronchoscopy and real-time imaging enabling safer, more precise access to peripheral lung lesions. These innovations allow clinicians to combine diagnostic and therapeutic procedures in a single setting.
