News
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Nerandomilast opens the door for potential monotherapy, add-on therapy for pulmonary fibrosis
Positive results from the FIBRONEER trials of nerandomilast in IPF and PPF have sent the phosphodiesterase 4B inhibitor to the FDA for marketing approval. If approved, nerandomilast would be the first new antifibrotic agent for ILD in more than a decade.
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Prevention of COPD exacerbations with an eosinophilic endotype
With the recent US approval of the IL-5-directed monoclonal antibody mepolizumab as an add-on therapy for patients with COPD, the era of COPD biologics is undeniably here.
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Moderate to severe OSA increases risk of severe COVID-19
According to critical care specialist Lina Miyakawa, MD, FCCP, the findings are a reminder that OSA “is not just a sleep disorder but a systemic condition with meaningful public health implications.”
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Tezepelumab found to reduce oral corticosteroid use in severe asthma
The WAYFINDER study shows a clinically meaningful reduction in oral corticosteroid dosing, which may allow patients to get off steroids, said pulmonology expert Stephen T. Doyle, DO, MBA, FCCP.
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New data confirms ILD as lung cancer risk factor
Bradford C. Bemiss, MD, and Claudia Henschke, PhD, MD, said the study clearly shows patients with interstitial lung disease have an increased risk of lung cancer.
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Coping styles linked to cognitive complaints in OSA
Investigator Tim J.A. Vaessen, MSc, said the findings suggest clinicians should look beyond sleep apnea and mood symptoms when evaluating cognitive complaints.
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Persistent mucus plugs linked to faster lung function decline in COPD
Investigator Sofia Mettler, MD, MPH, said the findings may point to a potential intervenable pathology in obstructive airway disease.
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Noninferiority data move navigational bronchoscopy into frontline lung biopsy discussion
Given the favorable safety profile seen in the VERITAS trial, investigator Matthew C. Aboudara, MD, FCCP, said the approach should be considered alongside CT scan-guided transthoracic needle biopsy.
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Varenicline found effective for nicotine vaping cessation in youth
Researcher A. Eden Evins, MD, said she was surprised by the ineffectiveness of behavioral therapy alone.
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Oseltamivir beats supportive care for patients hospitalized with seasonal influenza
Investigator Anthony Bai, MD, MSc, and infectious disease expert Christina Thornton, MD, PhD, discuss a large analysis that showed an in-hospital mortality rate of 3.5% for oseltamivir vs 4.9% for supportive care.
