CHEST Physician
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Matters of the right heart: Applying the 2025 ASE guidelines in PH practice
The latest guidelines from the American Society of Echocardiography emphasize three pillars of right-heart assessment: structure, function, and hemodynamics.
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Top reads from the CHEST journal portfolio – October 2026
Read new research from the journal portfolio on predicting clinical response to benralizumab using imaging, using machine learning to develop a risk score for ventilator-assisted pneumonia, and evaluating efficacy of omadacycline for MABC pulmonary disease.
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Selpercatinib improves event-free survival in early-stage RET fusion-positive NSCLC
Alexander E. Drilon, MD, discusses the findings from the first randomized phase 3 trial to evaluate a RET kinase inhibitor as adjuvant therapy in RET fusion-positive lung cancer.
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Intensive antiviral chemoprophylaxis in nursing homes reduces hospitalization
“The actionable message is not to aim for 100%; it is to reach the most residents in the first 48 hours,” said Viren Kaul, MD, FCCP.
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Remote patient monitoring shows no benefit after serious infections, major trial finds
Researcher Sachin Yende, MD, MS, said the results challenge the assumption that remote monitoring alone improves postdischarge outcomes.
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Limited data on GLP-1RAs show early promise in PAH
A review led by Benoît Aguado, MD, explores several mechanisms that could make GLP-1 receptors relevant to pulmonary vascular disease.
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Atelectasis in peripheral bronchoscopy
Atelectasis remains one of the greatest challenges during robotic bronchoscopy, reducing diagnostic accuracy and obscuring peripheral lung lesions. Learn how evidence-based ventilatory and positioning strategies can minimize atelectasis, improve tool-in-lesion confirmation, and enhance procedural success.
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Sleep in the ICU: Why closed eyes do not mean rest
Unconsciousness is not synonymous with sleep. Available evidence increasingly supports treating sleep as an essential component of ICU care rather than a secondary comfort measure.
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Severe valvular dysfunction in critically ill patients
Prompt diagnosis of acute severe valvular disease and tailored medical, ventilatory, and mechanical circulatory support can help stabilize patients as a bridge to definitive valve intervention.









