CHEST Physician
-
Study finds triple combination modulator therapy reduces inflammation in CF
Valentino Bezzerri, PhD, discusses findings from a compassionate-use study examining the effects of elexacaftor/tezacaftor/ivacaftor on inflammation in patients with cystic fibrosis.
-
Bringing the ICU to the patient: ECMO transport programs as high-reliability systems
ECMO transport programs represent an evolution toward networked critical care, extending advanced critical care beyond fixed, tertiary care centers.
-
Airway complications post-lung transplant: Risk factors, outcomes, and interventions
Early detection and phenotype-driven bronchoscopic management are key to improving outcomes in patients with airway complications after undergoing lung transplantation.
-
When norepinephrine isn’t enough: Managing vasoplegic shock
Early recognition and structured escalation of therapy are essential in vasoplegic shock, as prompt restoration of vascular tone remains critical to reversing shock and improving patient outcomes.
-
Top reads from the CHEST journal portfolio – April 2026
Read new research from the journal portfolio on inhaler substitutions at the VA, the impact of clot burden in patients with PE, and continuous opioid infusion for comfort-focused care in the ICU.
-
Real-world data show adherence to nodal dissection standard improves detection of lymph node involvement in patients with NSCLC
Increased lymph node analysis was associated with a 2.1% absolute increase in pathologic nodal upstaging, according to recent research.
-
Study links nocturnal GERD, undiagnosed OSA to worse outcomes in IPF
Researchers said the findings support evaluation of sleep‑related comorbidities to identify potentially modifiable contributors to symptoms and physiologic impairment.
-
Effects of LAMA or ICS withdrawal may increase risk for COPD exacerbations
Discontinuing LAMA or ICS treatment may more than double the risk of exacerbations for up to 90 days, according to an analysis by Alexander Mathioudakis, MD, PhD.
-
RSV hospitalization increases cardiorespiratory event, COPD exacerbation risk
Caihua Liang, MD, PhD, and Elizabeth Begier, MD, discuss the importance of prevention in light of data showing elevated risk for up to 180 days following the acute infection.
-
Navigating AI’s emerging role in critical care
AI tools like OpenEvidence are changing the way critical care clinicians learn, study, and practice medicine in the ICU setting.
