CHEST Physician
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Precision immunotherapy for sepsis improves early organ dysfunction, study shows
Researcher Evangelos J. Giamarellos-Bourboulis, MD, PhD, said the conventional wisdom that patients start with hyperinflammation and progress to immunoparalysis is being called into question by the results.
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Retrospective study confirms RSV, flu significantly increase hospitalization risk in pediatric patients
The study showed that children with comorbidities are at the highest risk, with a fivefold increase in severe outcomes.
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Rapid RSV testing may reduce antibiotic use in pediatric respiratory infections
Riccardo Boracchini, MSc, said the study provides some of the strongest evidence to date that rapid diagnostic testing can reduce antibiotic use outside the hospital setting.
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Link between viral pneumonia, lung cancer risk underlies importance of vaccination against respiratory infections
New data add weight to the case for protecting against respiratory viruses as part of lung cancer prevention.
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Future directions of thoracic ultrasonography in the management of pleural effusions
There is potential to reduce reliance on CT imaging and patient radiation exposure, decrease the need for invasive diagnostic procedures, and enhance diagnostic precision.
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Rethinking pediatric home mechanical ventilation
Persistent disparities in caregiver burden, home nursing shortages, and access to resources highlight the need for standardized education, telemedicine integration, and national safety infrastructure.
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Precision pharmacotherapy in OSA: Promise, progress, and readiness
Sleep medicine is entering a promising era in which individualized, endotype-driven therapy is increasingly feasible, with emerging pharmacologic treatments targeting the diverse mechanisms underlying OSA.
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Pulmonary rehabilitation in ILD and PH: Expanding access beyond the center
Pulmonary rehabilitation remains one of the most effective interventions available for chronic respiratory disease. The research has shown a need for structured long-term maintenance programs for patients with ILD and PH.
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Psilocybin-assisted therapy bests nicotine patch for smoking cessation in pilot study
At six months following the target quit date, 40.5% of participants in the psilocybin group achieved biochemically verified prolonged abstinence compared with only 10.0% in the nicotine patch group.
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Updated sepsis guidelines balance rapid treatment initiation, antibiotic stewardship
In some cases, the new recommendations support treatment initiation before a patient reaches the hospital, while allowing flexibility in other cases to delay treatment until a sepsis diagnosis is confirmed.
