CHEST Physician
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Biologic treatment expansion leads to population-level reductions in asthma exacerbations
Findings show that beginning in 2015, annual exacerbation events decreased by 474.1 events per 1,000 patients per year and have continued to decline by 206.5 events per 1,000 patients per year.
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Influenza vaccination linked to lower risk of pediatric death across nine US seasons
A recent CDC analysis showed 80% vaccine effectiveness against influenza-associated death in children.
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Randomized trial reports lower noninvasive ventilation failure with nasal intermittent positive airway pressure in preterm infants
Alexander Gipsman, MD, said the study makes a strong case for use of nasal intermittent positive pressure ventilation for infants with respiratory distress syndrome.
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Oxygen-sensitive and fixed components of pulmonary vascular load
Three situations illustrate the pulmonary vasculature’s physiologic response to hypoxia: chronic lung disease, high-altitude pulmonary hypertension, and pulmonary arterial hypertension in patients living at high altitude.
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The needle and the lesion: Navigating a patient’s fear of tumor seeding
It is important to acknowledge patient fears while also reassuring them that while tumor dissemination during biopsy is biologically plausible, the clinical risk is exceedingly low.
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FDA approval of oveporexton for narcolepsy allows clinicians to treat more than symptoms
When the US Food and Drug Administration approved the drug in August, oveporexton became the first agent to target the loss of orexin signaling that causes narcolepsy type 1.
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Study shows association between higher vitamin A levels and better lung function
The results linked higher vitamin A levels with better lung function in children and adults with asthma, while vitamin D showed a similar association primarily in adults.
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Point-of-care respiratory virus testing in nursing homes could reduce transfers to EDs
A recent study showed that onsite POC-RM-PCR testing resulted in an 11% absolute reduction in the probability of emergency department transfer during an outbreak.
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Low-nicotine cigarettes unlikely to trigger sustained compensatory smoking, meta-analysis finds
Hasmeena Kathuria, MD, said the findings provide further support that very low nicotine content cigarettes do not lead to substantially increased smoking or carbon monoxide exposure.
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Air pollution and dysglycemia: Implications for pulmonary practice
Air pollution exposure is linked to incident diabetes and adverse glycemic biomarkers. Clinicians can help patients assess their exposure and provide practical counseling.
