CHEST Physician
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Precision pharmacotherapy in OSA: Promise, progress, and readiness
Sleep medicine is entering a promising era in which individualized, endotype-driven therapy is increasingly feasible, with emerging pharmacologic treatments targeting the diverse mechanisms underlying OSA.
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Pulmonary rehabilitation in ILD and PH: Expanding access beyond the center
Pulmonary rehabilitation remains one of the most effective interventions available for chronic respiratory disease. The research has shown a need for structured long-term maintenance programs for patients with ILD and PH.
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Psilocybin-assisted therapy bests nicotine patch for smoking cessation in pilot study
At six months following the target quit date, 40.5% of participants in the psilocybin group achieved biochemically verified prolonged abstinence compared with only 10.0% in the nicotine patch group.
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Updated sepsis guidelines balance rapid treatment initiation, antibiotic stewardship
In some cases, the new recommendations support treatment initiation before a patient reaches the hospital, while allowing flexibility in other cases to delay treatment until a sepsis diagnosis is confirmed.
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Small trial shows lower ARDS rate, mortality with sivelestat following cardiopulmonary bypass
Nicholas Villalobos, MD, said that while sivelestat may not represent a single solution for ARDS, evidence that it can temper the inflammatory cascade is positive.
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When less is more: Ultrasound’s role in deresuscitation
Certain bedside ultrasound techniques may help guide fluid deresuscitation in septic shock by identifying pulmonary and venous congestion in real time.
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An unfortunate necessity: The DME moratorium and the future of out-of-hospital respiratory care
The DME moratorium from CMS is justified but fails to address inherent problems within the system itself.
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LGBTQ+ health in focus: A Pride Month call to action
Let us recommit to a principle of care that surpasses clinical excellence; one that is inclusive, compassionate, and just.
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Top reads from the CHEST journal portfolio – May 2026
Read new research from the journal portfolio on proximal hypoglossal nerve stimulation, shared decision-making in lung cancer screening, and lactate clearance in postoperative cardiac surgery care.
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Advocating for change based on pulse oximetry research
Thomas Valley, MD, MS, shares how he advocates for systemwide change based on his research in pulse oximeter inaccuracies due to skin tone and encourages other clinicians to ask important questions that will improve patient care.
