CHEST Physician
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EBUS nodal staging in early-stage non-small cell lung cancer
EBUS-TBNA disrupted the field of bronchoscopy by offering a minimally invasive, real-time imaging approach to biopsy, but recent data have emerged that show routine use of EBUS may warrant scrutiny.
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Considerations for single parents with terminal illness
Clinicians often focus more on what happens in the hospital than on issues beyond the hospital. This article covers the complex end-of-life issues that clinicians should consider for seriously ill patients with minor children.
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Top reads from the CHEST journal portfolio – August 2025
Editorial Board members share their insights on the TARGET trial results for robotic-assisted bronchoscopy, epidemiologic features of endotracheal tube obstruction, and weight management services for patients with OSA and obesity.
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ORCA-3 replicates strong tobacco cessation results for cytisinicline
The ORCA-3 trial demonstrated that cytisinicline, a reformulated compound, significantly outperformed placebo by nearly six times in helping adults who smoke to quit.
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Study shows earlier vasopressin initiation for sepsis reduced in-hospital mortality
Critical care expert Natalie Achamallah, MD, FCCP, said OVISS data support guidelines that recommend earlier vasopressin as well as lower norepinephrine doses.
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EHR data confirm effectiveness of RSV vaccine in adults aged 60 and older
Pauline Terebuh, MD, MPH, said the results aligned with previous trials; however, Shaun J. Grannis, MD, said more data are needed to determine the durability of the protection.
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Oral medications for sleep in nonintubated ICU patients and their impact on delirium
Clinicians rank pharmacologic sleep aids for ICU patients who are not intubated, beginning with those that have the strongest evidence for safety and efficacy.
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Medical preparedness and critical care for the 2026 FIFA World Cup
In 2026, the FIFA World Cup will land in North America, whose health care infrastructure must be equipped to handle infectious disease threats, health care surges, mass casualty events, routine injuries, and chronic conditions.
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Sex as a factor in endotracheal tube and tidal volume selection
Accounting for a patient’s sex and, by extension, height when considering invasive mechanical ventilation can inform personalized medicine in two key ways: endotracheal tube selection and tidal volume selection.
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Denied, delayed, distressed
Prior authorization was designed to control costs and ensure appropriate care—but for many patients and clinicians, it causes treatment delays, denials, and administrative burdens.
