CHEST Physician
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Biologic therapies in asthma: From foundation to the future
Biologic therapies are changing severe asthma management, shifting the goal from control to remission. Diego J. Maselli, MD, FCCP; Dharani Narendra, MD, FCCP; and Megan Conroy, MD, MAEd, FCCP, explore their impact in this installment of Clinical Outlook in Pulmonology.
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Bilateral lung transplant comparable to heart-lung transplant in primary PAH
Recent findings reinforce the widely used strategy of bilateral lung transplantation for most patients with primary PAH who do not have structural heart disease.
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Intranasal saline improves symptoms in children with sleep-disordered breathing
The results of the MIST+ trial support the conclusion that saline is as effective as corticosteroid in managing symptoms of OSDB, said lead author Gillian Nixon, MD.
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Inside the 2025 CPR and ECC guideline updates from the AHA
Ashish Panchal, MD, PhD, and Daniel Arellano, PhD, RN, APRN, ACNP-BC, review new guidelines that prioritize improved survival rates and neurological outcomes.
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A ‘central’ issue in sleep medicine
An AASM task force recently published guidelines on central sleep apnea management, which includes recommendations on whether adaptive servo-ventilation is a safe option in these patients.
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Beyond ‘doing everything’: Moral distress, burnout, and the emotional toll of ICU care
ICU burnout and morally distressing end-of-life care are intertwined, making improved end-of-life care both a patient imperative and a clinician necessity.
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Light therapy to improve sleep in older patients with dementia
A comprehensive approach combining light therapy with daytime physical activity and sleep-wake scheduling has significant benefits for patients with dementia.
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Top reads from the CHEST journal portfolio – March 2026
Read new research from the journal portfolio on dietary interventions in patients with fibrotic ILD, rapid metagenomic sequencing of bronchoalveolar lavage fluid, and corticosteroid regimens for COVID-19 with ARDS.
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Adult bronchiectasis guidelines updated to reflect emerging evidence on disease identification and management
New bronchiectasis recommendations from the European Respiratory Society reflect a shift toward individualized, risk-based care, recognizing diverse inflammatory and microbiologic profiles. The guidelines emphasize early identification of high-risk patients, multidimensional assessment, and universal airway clearance training.
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Black lung disease mortality on the rise, recent analysis shows
CDC experts David N. Weissman, MD, FCCP, and Jacek Mazurek, MD, PhD, said that identifying dust exposure is key to improving outcomes for patients with coal workers’ pneumoconiosis.
