Critical Care
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Updated sepsis guidelines balance rapid treatment initiation, antibiotic stewardship
In some cases, the new recommendations support treatment initiation before a patient reaches the hospital, while allowing flexibility in other cases to delay treatment until a sepsis diagnosis is confirmed.
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Small trial shows lower ARDS rate, mortality with sivelestat following cardiopulmonary bypass
Nicholas Villalobos, MD, said that while sivelestat may not represent a single solution for ARDS, evidence that it can temper the inflammatory cascade is positive.
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When less is more: Ultrasound’s role in deresuscitation
Certain bedside ultrasound techniques may help guide fluid deresuscitation in septic shock by identifying pulmonary and venous congestion in real time.
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Navigating normotensive shock
Authors discuss the role normotensive shock plays in PE risk stratification according to new AHA guidelines on PE classification and management.
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Advancing excellence: Why I pursued the CHEST CCAPP certification
The CCAPP certification demonstrates not only competence but also commitment to patients, teams, and the profession.
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Study supports early TB therapy to reduce sepsis mortality in HIV
The ATLAS team of researchers said that because typical sepsis treatment does not target TB, clinicians should consider immediate TB treatment for people with HIV-related sepsis.
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When norepinephrine isn’t enough: Managing vasoplegic shock
Early recognition and structured escalation of therapy are essential in vasoplegic shock, as prompt restoration of vascular tone remains critical to reversing shock and improving patient outcomes.
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RSV hospitalization increases cardiorespiratory event, COPD exacerbation risk
Caihua Liang, MD, PhD, and Elizabeth Begier, MD, discuss the importance of prevention in light of data showing elevated risk for up to 180 days following the acute infection.
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Navigating AI’s emerging role in critical care
AI tools like OpenEvidence are changing the way critical care clinicians learn, study, and practice medicine in the ICU setting.
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Beyond ‘doing everything’: Moral distress, burnout, and the emotional toll of ICU care
ICU burnout and morally distressing end-of-life care are intertwined, making improved end-of-life care both a patient imperative and a clinician necessity.
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Beyond the blueprint: Early outcomes from the CHEST Critical Care APP certification exam
The 2025 exam tells a clear story: APPs are seeking meaningful validation, value lifelong learning, and want credentials that reflect the realities of modern critical care.
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Mechanical power as a target for lung protective ventilation
Mechanical power-based strategies aim to minimize unnecessary power delivery and reduce harm. Review how to measure and use this metric and what challenges it poses.












