CHEST Physician
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Triple therapy shows meaningful benefits in uncontrolled asthma
Alberto Papi, MD, FCCP, said recent data from the KALOS and LOGOS trials suggest triple therapy may address airflow limitation and exacerbation risk in a single inhaler.
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Phase 3 TETON trials demonstrate positive results for inhaled treprostinil for IPF
Steven D. Nathan, MD, FCCP, said the evidence shows the drug is effective for treating pulmonary hypertension and may slow or prevent fibrosis progression.
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Study supports early TB therapy to reduce sepsis mortality in HIV
The ATLAS team of researchers said that because typical sepsis treatment does not target TB, clinicians should consider immediate TB treatment for people with HIV-related sepsis.
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Data show oral nalbuphine significantly reduces chronic cough in idiopathic pulmonary fibrosis
Experts discuss the promising results—particularly surrounding patient-reported outcomes in this population—and the need for long-term safety data.
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Large, longitudinal study adds to evidence that links OSA to mental health disorder
Colin Huntley, MD, said the data help to confirm what many have seen in the clinic and suggest that patients may see mental health improvements if their sleep apnea is better managed.
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Study finds triple combination modulator therapy reduces inflammation in CF
Valentino Bezzerri, PhD, discusses findings from a compassionate-use study examining the effects of elexacaftor/tezacaftor/ivacaftor on inflammation in patients with cystic fibrosis.
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Bringing the ICU to the patient: ECMO transport programs as high-reliability systems
ECMO transport programs represent an evolution toward networked critical care, extending advanced critical care beyond fixed, tertiary care centers.
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Airway complications post-lung transplant: Risk factors, outcomes, and interventions
Early detection and phenotype-driven bronchoscopic management are key to improving outcomes in patients with airway complications after undergoing lung transplantation.
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When norepinephrine isn’t enough: Managing vasoplegic shock
Early recognition and structured escalation of therapy are essential in vasoplegic shock, as prompt restoration of vascular tone remains critical to reversing shock and improving patient outcomes.
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Top reads from the CHEST journal portfolio – April 2026
Read new research from the journal portfolio on inhaler substitutions at the VA, the impact of clot burden in patients with PE, and continuous opioid infusion for comfort-focused care in the ICU.
